Best Medicine Episode 4 Release Date, Time, Cast, And Streaming Details

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The next chapter in Dr. Martin Best’s story arrives this week on Fox. Best Medicine Episode 4 is scheduled to air on Tuesday, January 27, 2026. New episodes of the medical dramedy air weekly on Tuesdays at 8:00 PM Eastern Time (ET) and 5:00 PM Pacific Time (PT) on the Fox network. The episode is titled “All the World’s Ablaze”.

Best Medicine Episode 4 Release And Streaming Schedule

Viewers can watch Episode 4 when it premieres on the Fox network. For those who stream their shows, the episode will be available on Hulu the next day, Wednesday, January 28. This follows the standard release pattern for the series, where episodes stream on Hulu after their initial Fox broadcast.

International viewers should check their local Fox-affiliated channels or streaming platforms for specific release times in their region.

Where To Watch Best Medicine Online

The primary way to watch new episodes is through the Fox broadcast. If you miss the live airing, here are your options:

  • Hulu: The streaming home for Best Medicine. New episodes are added to Hulu the day after they air on Fox.
  • Fox Website and App: Fox typically makes the latest episodes available for streaming on its official website and mobile app, Fox One, the day after they air. A cable provider login is usually required.
  • Live TV Streaming Services: Services that include Fox in their channel lineup, such as YouTube TV, Hulu + Live TV, FuboTV, and DirecTV Stream, will allow you to watch the episode live as it airs or from their cloud DVR libraries.

Best Medicine Episode 4 Cast And Characters

The series features an ensemble cast led by Josh Charles as the brilliant but brusque Dr. Martin Best. He is joined by main cast members:

  • Abigail Spencer as Louisa Gavin, the local schoolteacher.
  • Josh Segarra as Sheriff Mark Mylow, Louisa’s ex-fiancรฉ.
  • Cree as Elaine Denton, Dr. Best’s enthusiastic administrative assistant.
  • Annie Potts as Aunt Sarah, Martin’s aunt and the town’s lobster fisherwoman.

The show also features a roster of recurring characters who populate the quirky fishing village of Port Wenn, Maine. These include Stephen Spinella and Jason Veasey as married restaurant owners Greg Garrison and George Brady, John DiMaggio and Carter Shimp as contractors Bert Large and his son Al, and Clea Lewis as pharmacist Sally Mylow. A special guest star in the series is Martin Clunes, the original star of the British Doc Martin, who appears as Dr. Best’s father, Dr. Robert Best.

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What Best Medicine Is About

Best Medicine is an American adaptation of the long-running and beloved British series Doc Martin. The story follows Dr. Martin Best, a top surgeon who suddenly leaves his high-pressure career in Boston. He moves to the small, fictional fishing village of Port Wenn, Maine, where he spent summers as a child, to become the town’s only general practitioner.

Martin struggles with a debilitating blood phobia and a blunt, often rude bedside manner that constantly clashes with the town’s needy and eccentric residents. Despite wanting to be left alone, he continually finds himself involved in the personal dramas and mysteries of the community. The core question of the series is whether this challenging town and its people might be the unlikely cure for the doctor’s own personal issues.

“I donโ€™t care about silly little festivals or gossip like everyone else in this town. Iโ€™m here to work,” says Josh Charles as Dr. Martin Best in the show’s official trailer, perfectly capturing his character’s irritable fish-out-of-water attitude.

What To Expect From The New Season

The first three episodes have established Dr. Best’s difficult arrival in Port Wenn and his rocky start with the locals, including schoolteacher Louisa Gavin. Episode 3, “Take Me Out of the Ballgame,” aired on January 20.

As the season continues, viewers will see more of the town’s unique characters and the medical or personal puzzles they bring to Dr. Best’s door. The dynamic between Martin and Louisa is a central thread, as is Martin’s effort to manage his phobia while being the only doctor for miles. The upcoming appearance of Martin Clunes as Dr. Best’s father is also a anticipated story point for fans of the original series.

The series is executive produced by Ben Silverman, Liz Tuccillo (who also developed the adaptation), and original Doc Martin producers Mark Crowdy and Philippa Braithwaite, ensuring a connection to the spirit of the UK hit.

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