A major power shift is rocking the world of “Gen V,” and it comes from the smartest person on the planet. Sister Sage, the super-genius from “The Boys,” has officially taken over as the CEO of Vought International. Her new role, revealed in the show’s fifth episode, positions her as a key player manipulating events both in the boardroom and at Godolkin University, setting the stage for an explosive conflict.
Who Is Sister Sage?
Played by Susan Heyward, Sister Sage first appeared in “The Boys” Season 4 as a member of The Seven. Unlike most superheroes who rely on physical strength, her power is her superhuman intellect. She can strategize, predict outcomes, and manipulate situations with terrifying accuracy.
Her background reveals a deep-seated distrust of institutions. As a child, she discovered a cure for her grandmother’s leukemia, but doctors dismissed her work, leading to her grandmother’s painful death. This tragedy shaped her cynical view of humanity and her belief that people are essentially “animals” who don’t deserve help.
โI could cure cancer, reverse global warming, but what’s the point? Humans are animals. And the lines at Voughtland are too long as it is,โ she once told Victoria Neuman.
Sage’s Role in Gen V Season 2
Sister Sage’s influence is felt immediately in “Gen V” Season 2. She appears in Episode 5, which aired on October 1, 2025, and her arrival changes everything.
Her most significant move is replacing Ashley Barrett as the head of Vought. When discussing the leadership change, Sage coolly states that Ashley “certainly can’t” be CEO anymore, “not in her state,” a reference to Ashley injecting herself with Compound V at the end of “The Boys” Season 4.
Beyond the corporate takeover, Sage has a close and mysterious partnership with Dean Cipher, the new and manipulative dean of Godolkin University. Their alliance suggests a shared, long-term goal that involves the students, particularly Marie Moreau.
The Plan for Marie Moreau
Dean Cipher has been intensely focused on pushing Marie to unlock the full potential of her blood-manipulation powers. With Sister Sage now in the picture, their plan accelerates. In a key scene from Episode 5, Sage provides Cipher with a “gift” to change the variables of his experiments.
This gift turns out to be Marie’s sister, Annabeth. The traumatic situation of finding her sister apparently dead forces Marie to tap into a terrifying new level of her powerโshe not only heals Annabeth’s fatal wound but seemingly brings her back to life.
This breakthrough is exactly what Cipher and Sage wanted. They see in Marie a power that could potentially rival Homelander’s. Sage recognizes that Homelander is an unstable weapon, and she and Cipher appear to be creating a countermeasure they can control.
A Connection to The Boys Season 5
Sister Sage’s actions in “Gen V” create a direct narrative bridge to the upcoming final season of “The Boys.” By becoming CEO of Vought, she gains immense power to shape the future conflict between humans and Supes.
Her work with Cipher at Godolkin University, especially the experiments on Marie, is likely a crucial part of a larger strategy. Having helped Homelander rise to power, she now seems to be preparing for a world where he is no longer in control, positioning herself at the center of the coming storm.
Also Read: Gen V Season 2: Meet the New Supes and Their Powers
Credits: IGN
